Chonluten
Also known as: Glu-Asp-Gly, EDG
At a glance
PeptiGuide dataset · reviewed Aug 2026
What it is
Synthetic EDG tripeptide researched as a respiratory bioregulator
Status
Preclinical
Typical dose
10–20mg
Researched for
Respiratory health, lung function, bronchial support
Trial progress
- PrePreclinical
- IPhase I
- IIPhase II
- IIIPhase III
- IVPhase IV
- FDAFDA approved
Preclinical - Promising animal research, limited human data
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In plain language
- Synthetic tripeptide also referred to as Glu-Asp-Gly or EDG.
- Positioned in the Khavinson bioregulator family and researched for respiratory tissue, lung function, and bronchial support.
- Source reports no FDA or EMA approval and describes the evidence base as or uncontrolled observational work.
- Reported dose patterns are 10-20 mg daily, once or twice daily, using oral capsules or sublingual administration.
- No registered randomized controlled human trials were reported in the supplied evidence.
How it's thought to work
Chonluten is presented under the Khavinson bioregulator framework, where short peptides are proposed to enter cells and influence nuclear gene-expression activity. For Chonluten specifically, the source links the hypothesis to respiratory epithelial tissue and genes related to stress response, antioxidant activity, and inflammation. The same evidence cautions that this remains a proposed mechanism, with uncertainty about whether free EDG reaches human nuclei at relevant concentrations or binds specific DNA regions in a clinically meaningful way.
What the research shows
Where the research stands
The supplied source connects Chonluten, the EDG tripeptide, to Khavinson-group work on bronchopulmonary tissue. It reports discussion of oral EDG in chronic bronchitis with an asthmatic component and mentions related work pairing EDG with Bronchogen in chronic obstructive pulmonary disease contexts. The evidence base is described as concentrated in one research network, with uncontrolled clinical observations, limited independent replication, no registered randomized controlled trials, and mechanistic claims relying on cell-culture or animal findings rather than confirmed human outcomes.
What it shows
✓ Animal studies
Promising animal research, limited human data
△ Limitations
Animal study doses may not translate directly to humans.
Bottom line: Preclinical research; reported supplement approval in Russia; not FDA or EMA approved Not FDA approved
Typical dosing
CommunityCommunity dataset10–20 mg
daily
Community-reported use frames Chonluten as a lung-tissue bioregulator for respiratory support. This is not a medical dosing recommendation.
Research dosing
Animal studies onlyAnimal studies only - may not translate to humans
Doses observed in studies
10-20 mg daily
Animal study doses may not translate directly to humans.
- Duration
- 10-30 day cycles
- Administration
- Oral capsules or sublingual
Timing & administration
Best time to take
Morning on an empty stomach
Once or twice daily
Food recommendation
Take on an empty stomach
Why this timing?
The source says this class is commonly timed away from food to support absorption; this is a reported timing rationale rather than a proven clinical requirement.
Possible side effects
Not everyone experiences these. Individual responses vary with dose, duration, and personal factors.
- Generally well tolerated in the source report
- Limited safety data outside Russia
- Not FDA approved
Not everyone experiences side effects, and severity can vary by context, purity, route, and individual health factors.
Sources
Frequently asked questions
Sequence
H-Glu-Asp-Gly-OH (EDG)
One open dataset
Every fact on this page - doses, side effects, references - comes from the same PeptiGuide dataset that powers the Tracker, Compare, and the Lab.
Browse the datasetEducational resource, not medical advice. Talk to your clinician before acting on anything here.
Community discussion
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